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Label-free microfluidic characterization of temperature-dependent biomolecular interactions

We present a microfluidic approach to characterizing temperature-dependent biomolecular interactions. Solvated L-arginine vasopressin (AVP) and its immobilized RNA aptamer (spiegelmer) were allowed to achieve equilibrium binding in a microchip at a series of selected temperatures. Unbound AVP were c...

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Main Authors: Nguyen, ThaiHuu, Pei, Renjun, Landry, Donald W., Stojanovic, Milan N., Lin, Qiao
Format: Artigo
Jezik:Inglês
Izdano: American Institute of Physics 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170392/
https://ncbi.nlm.nih.gov/pubmed/21915242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.3620417
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