Pre-Clinical Efficacy and Safety of Experimental Vaccines Based on Non-Replicating Vaccinia Vectors against Yellow Fever

BACKGROUND: Currently existing yellow fever (YF) vaccines are based on the live attenuated yellow fever virus 17D strain (YFV-17D). Although, a good safety profile was historically attributed to the 17D vaccine, serious adverse events have been reported, making the development of a safer, more moder...

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Detalhes bibliográficos
Main Authors: Schäfer, Birgit, Holzer, Georg W., Joachimsthaler, Alexandra, Coulibaly, Sogue, Schwendinger, Michael, Crowe, Brian A., Kreil, Thomas R., Barrett, P. Noel, Falkner, Falko G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170363/
https://ncbi.nlm.nih.gov/pubmed/21931732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024505
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