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Ssn6–Tup1 interacts with class I histone deacetylases required for repression
Ssn6–Tup1 regulates multiple genes in yeast, providing a paradigm for corepressor functions. Tup1 interacts directly with histones H3 and H4, and mutation of these histones synergistically compromises Ssn6–Tup1-mediated repression. In vitro, Tup1 interacts preferentially with underacetylated isoform...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC317033/ https://ncbi.nlm.nih.gov/pubmed/11069890 |
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