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Activation of dormant origins of DNA replication in budding yeast

Eukaryotic genomes often contain more potential replication origins than are actually used during S phase. The molecular mechanisms that prevent some origins from firing are unknown. Here we show that dormant replication origins on the left arm of budding yeast chromosome III become activated when b...

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Bibliographic Details
Main Authors: Santocanale, Corrado, Sharma, Karuna, Diffley, John F.X.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 1999
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC317032/
https://ncbi.nlm.nih.gov/pubmed/10500092
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