Familial Adenomatous Polyposis-Associated Desmoids Display Significantly More Genetic Changes than Sporadic Desmoids

Desmoid tumours (also called deep or aggressive fibromatoses) are potentially life-threatening fibromatous lesions. Hereditary desmoid tumours arise in individuals affected by either familial adenomatous polyposis (FAP) or hereditary desmoid disease (HDD) carrying germline mutations in APC. Most spo...

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Hauptverfasser: Robanus-Maandag, Els, Bosch, Cathy, Amini-Nik, Saeid, Knijnenburg, Jeroen, Szuhai, Karoly, Cervera, Pascale, Poon, Raymond, Eccles, Diana, Radice, Paolo, Giovannini, Marco, Alman, Benjamin A., Tejpar, Sabine, Devilee, Peter, Fodde, Riccardo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170296/
https://ncbi.nlm.nih.gov/pubmed/21931686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024354
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