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Chiral gold(I) vs chiral silver complexes as catalysts for the enantioselective synthesis of the second generation GSK-hepatitis C virus inhibitor

The synthesis of a GSK 2(nd) generation inhibitor of the hepatitis C virus, by enantioselective 1,3-dipolar cycloaddition between a leucine derived iminoester and tert-butyl acrylate, was studied. The comparison between silver(I) and gold(I) catalysts in this reaction was established by working with...

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מידע ביבליוגרפי
Main Authors: Martín-Rodríguez, María, Nájera, Carmen, Sansano, José M, de Cózar, Abel, Cossío, Fernando P
פורמט: Artigo
שפה:Inglês
יצא לאור: Beilstein-Institut 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170196/
https://ncbi.nlm.nih.gov/pubmed/21915198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.7.111
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