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Control of Cyclin B1 localization through regulated binding of the nuclear export factor CRM1

Activation of the Cyclin B/Cdc2 kinase complex triggers entry into mitosis in all eukaryotic cells. Cyclin B1 localization changes dramatically during the cell cycle, precipitously transiting from the cytoplasm to the nucleus at the beginning of mitosis. Presumably, this relocalization promotes the...

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Auteurs principaux: Yang, Jing, Bardes, Elaine S.G., Moore, Jonathan D., Brennan, Jennifer, Powers, Maureen A., Kornbluth, Sally
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 1998
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC317017/
https://ncbi.nlm.nih.gov/pubmed/9679058
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