High-resolution localization of Drosophila Spt5 and Spt6 at heat shock genes in vivo: roles in promoter proximal pausing and transcription elongation

Recent studies have demonstrated roles for Spt4, Spt5, and Spt6 in the regulation of transcriptional elongation in both yeast and humans. Here, we show that Drosophila Spt5 and Spt6 colocalize at a large number of transcriptionally active chromosomal sites on polytene chromosomes and are rapidly rec...

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Détails bibliographiques

Publié dans:	Genes Dev
Auteurs principaux:	Andrulis, Erik D., Guzmán, Ernesto, Döring, Pascal, Werner, Janis, Lis, John T.
Format:	Artigo
Langue:	Inglês
Publié:	Cold Spring Harbor Laboratory Press 2000
Sujets:	Research Paper
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316984/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11040217/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.844200
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