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A Drosophila IκB kinase complex required for Relish cleavage and antibacterial immunity

Here we report the identification of a Drosophila IκB kinase complex containing DmIKKβ and DmIKKγ, homologs of the human IKKβ and IKKγ proteins. We show that this complex is required for the signal-dependent cleavage of Relish, a member of the Rel family of transcriptional activator proteins, and fo...

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Détails bibliographiques
Publié dans:Genes Dev
Auteurs principaux: Silverman, Neal, Zhou, Rui, Stöven, Svenja, Pandey, Niranjan, Hultmark, Dan, Maniatis, Tom
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2000
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316979/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11018014/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.817800
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