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Mitochondrial DNA copy number and risk of gastric cancer: a report from the Shanghai Women's Health Study

BACKGROUND: Mitochondrial DNA (mtDNA) are approximately 16,000bp circular double-stranded DNA molecules that are prime targets of oxidative damage. Several somatic mutations in mtDNA have been observed in gastric tumors suggesting an involvement in gastric cancer risk and progression. mtDNA copy num...

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Detalhes bibliográficos
Main Authors: Liao, Linda M., Baccarelli, Andrea, Shu, Xiao-Ou, Gao, Yu-Tang, Ji, Bu-Tian, Yang, Gong, Li, Hong-Lan, Hoxha, Mirjam, Dioni, Laura, Rothman, Nathaniel, Zheng, Wei, Chow, Wong-Ho
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169741/
https://ncbi.nlm.nih.gov/pubmed/21784958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-11-0379
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