Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization

Although the role of miR-200s in regulating E-cadherin expression and epithelial-mesenchymal transition is well established, their influence on metastatic colonization remains controversial. Here, we use clinical and experimental models of breast cancer metastasis to discover a pro-metastatic role o...

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Autors principals: Korpal, Manav, Ell, Brian J., Buffa, Francesca M., Ibrahim, Toni, Blanco, Mario A., Celià-Terrassa, Toni, Mercatali, Laura, Khan, Zia, Goodarzi, Hani, Hua, Yuling, Wei, Yong, Hu, Guohong, Garcia, Benjamin A., Ragoussis, Jiannis, Amadori, Dino, Harris, Adrian L., Kang, Yibin
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169707/
https://ncbi.nlm.nih.gov/pubmed/21822286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2401
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