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pha-4, an HNF-3 homolog, specifies pharyngeal organ identity in Caenorhabditis elegans

To build complex organs, embryos have evolved mechanisms that integrate the development of cells unrelated to one another by cell type or ancestry. Here we show that the pha-4 locus establishes organ identity for the Caenorhabditis elegans pharynx. In pha-4 mutants, pharyngeal cells are transformed...

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Autors principals: Horner, Michael A., Quintin, Sophie, Domeier, Mary Ellen, Kimble, Judith, Labouesse, Michel, Mango, Susan E.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC316969/
https://ncbi.nlm.nih.gov/pubmed/9649499
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