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A fused lasso latent feature model for analyzing multi-sample aCGH data

Array-based comparative genomic hybridization (aCGH) enables the measurement of DNA copy number across thousands of locations in a genome. The main goals of analyzing aCGH data are to identify the regions of copy number variation (CNV) and to quantify the amount of CNV. Although there are many metho...

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Detalhes bibliográficos
Main Authors: Nowak, Gen, Hastie, Trevor, Pollack, Jonathan R., Tibshirani, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169672/
https://ncbi.nlm.nih.gov/pubmed/21642389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxr012
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