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Identification of functional exonic splicing enhancer motifs recognized by individual SR proteins

Using an in vitro randomization and functional selection procedure, we have identified three novel classes of exonic splicing enhancers (ESEs) recognized by human SF2/ASF, SRp40, and SRp55, respectively. These ESEs are functional in splicing and are highly specific. For SF2/ASF and SRp55, in most ca...

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Autors principals: Liu, Hong-Xiang, Zhang, Michael, Krainer, Adrian R.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC316967/
https://ncbi.nlm.nih.gov/pubmed/9649504
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