Requirement of the CXXC Motif of Novel Francisella Infectivity Potentiator Protein B FipB, and FipA in Virulence of F. tularensis subsp. tularensis

The lipoprotein encoded by the Francisella tularensis subsp. tularensis locus FTT1103 is essential for virulence; an FTT1103 deletion mutant is defective in uptake and intracellular survival, and mice survive high dose challenges of greater than 10(8) bacteria. This protein has two conserved domains...

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Bibliographic Details
Main Authors: Qin, Aiping, Scott, David W., Rabideau, Meaghan M., Moore, Emily A., Mann, Barbara J.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169626/
https://ncbi.nlm.nih.gov/pubmed/21931773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024611
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