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A Soluble Factor from Trypanosoma cruzi Inhibits Transforming Growth Factor-ß-Induced MAP Kinase Activation and Gene Expression in Dermal Fibroblasts

The protozoan parasite Trypanosoma cruzi, which causes human Chagas' disease, exerts a variety of effects on host extracellular matrix (ECM) including proteolytic degradation of collagens and dampening of ECM gene expression. Exposure of primary human dermal fibroblasts to live infective T. cru...

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Detalhes bibliográficos
Main Authors: Mott, G. Adam, Costales, Jaime A., Burleigh, Barbara A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169535/
https://ncbi.nlm.nih.gov/pubmed/21931601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023482
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