Nuclear export of the small ribosomal subunit requires the Ran–GTPase cycle and certain nucleoporins
After their assembly in the nucleolus, ribosomal subunits are exported from the nucleus to the cytoplasm. After export, the 20S rRNA in the small ribosomal subunit is cleaved to yield 18S rRNA and the small 5′ ITS1 fragment. The 5′ ITS1 RNA is normally degraded by the cytoplasmic Xrn1 exonuclease, b...
Guardat en:
| Publicat a: | Genes Dev |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
1999
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316945/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10465789/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.16.2118 |
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