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Protein interactome reveals converging molecular pathways among autism disorders

To uncover shared pathogenic mechanisms among the highly heterogeneous autism spectrum disorders (ASDs), we developed a protein interaction network that identified hundreds of new interactions among proteins encoded by ASD-associated genes. We discovered unexpectedly high connectivity between SHANK...

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Autori principali: Sakai, Yasunari, Shaw, Chad A., Dawson, Brian C., Dugas, Diana V., Al-Mohtaseb, Zaina, Hill, David E., Zoghbi, Huda Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169432/
https://ncbi.nlm.nih.gov/pubmed/21653829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3002166
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