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Functional interactions of Prp8 with both splice sites at the spliceosomal catalytic center

A U5 snRNP protein, hPrp8, interacts closely with the GU dinucleotide at the 5′ splice site (5′SS), forming a specific UV-inducible cross-link. To test if this physical contact between the 5′SS and the carboxy-terminal region of Prp8 reflects a functional recognition of the 5′SS during spliceosome a...

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Autores principales: Siatecka, Miroslawa, Reyes, José L., Konarska, Maria M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 1999
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC316927/
https://ncbi.nlm.nih.gov/pubmed/10444596
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