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Pds1p of budding yeast has dual roles: inhibition of anaphase initiation and regulation of mitotic exit

Progression through mitosis is controlled by protein degradation that is mediated by the anaphase-promoting complex/cyclosome (APC/C) and its associated specificity factors. In budding yeast, APC/C(Cdc20) promotes the degradation of the Pds1p anaphase inhibitor at the metaphase-to-anaphase transitio...

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Bibliographic Details
Published in:Genes Dev
Main Authors: Cohen-Fix, Orna, Koshland, Doug
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 1999
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316926/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10444593/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.15.1950
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