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The central cavity in trimeric glutamate transporters restricts ligand diffusion
A prominent aqueous cavity is formed by the junction of three identical subunits in the excitatory amino acid transporter (EAAT) family. To investigate the effect of this structure on the interaction of ligands with the transporter, we recorded currents in voltage-clamped Xenopus oocytes expressing...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3169134/ https://ncbi.nlm.nih.gov/pubmed/21873219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1108785108 |
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