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Unproductively spliced ribosomal protein mRNAs are natural targets of mRNA surveillance in C. elegans

Messenger RNA surveillance, the selective and rapid degradation of mRNAs containing premature stop codons, occurs in all eukaryotes tested. The biological role of this decay pathway, however, is not well understood. To identify natural substrates of mRNA surveillance, we used a cDNA-based representa...

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Autors principals: Mitrovich, Quinn M., Anderson, Philip
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC316897/
https://ncbi.nlm.nih.gov/pubmed/10970881
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