Development of an Interferon-Gamma ELISPOT Assay to Detect Human T Cell Responses to HSV-2

The need for an HSV-2 vaccine is great considering the increasing prevalence of HSV-2 despite the widespread use of antiviral drugs. Human clinical trials of HSV-2 vaccines that elicit neutralizing antibodies have proven to be only partially effective suggesting that induction of effective T cell re...

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Hauptverfasser: Posavad, Christine M., Magaret, Amalia S., Zhao, Lin, Mueller, Dawn E., Wald, Anna, Corey, Lawrence
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3168963/
https://ncbi.nlm.nih.gov/pubmed/21801778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.07.028
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