Relationship Between CYP2A6 and CHRNA5-CHRNA3-CHRNB4 Variation and Smoking Behaviors and Lung Cancer Risk

Genetic variations in the CYP2A6 nicotine metabolic gene and the CHRNA5-CHRNA3-CHRNB4 (CHRNA5-A3-B4) nicotinic gene cluster have been independently associated with lung cancer. With genotype data from ever-smokers of European ancestry (417 lung cancer patients and 443 control subjects), we investiga...

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Bibliografiske detaljer
Main Authors: Wassenaar, Catherine A., Dong, Qiong, Wei, Qingyi, Amos, Christopher I., Spitz, Margaret R., Tyndale, Rachel F.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2011
Fag:
Brief Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3168937/
https://ncbi.nlm.nih.gov/pubmed/21747048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djr237
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