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Unraveling a cytoplasmic role for hnRNP D in the in vivo mRNA destabilization directed by the AU-rich element

AU-rich RNA-destabilizing elements (AREs) have become a paradigm for studying cytoplasmic mRNA turnover in mammalian cells. Though many RNA-binding proteins have been shown to bind to AREs in vitro, trans-acting factors that participate in the in vivo destabilization of cytoplasmic RNA by AREs remai...

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Published in:Genes Dev
Main Authors: Loflin, Paul, Chen, Chyi-Ying A., Shyu, Ann-Bin
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 1999
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Research Paper
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316883/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10421639/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.14.1884
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