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AKAPs: The Architectural Underpinnings of Local cAMP signaling

The cAMP-dependent protein kinase A (PKA) is targeted to specific compartments in the cardiac myocyte by A-kinase anchoring proteins (AKAPs), a diverse set of scaffold proteins that have been implicated in the regulation of excitation-contraction coupling and cardiac remodeling. AKAPs bind not only...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kritzer, Michael D., Li, Jinliang, Dodge-Kafka, Kimberly, Kapiloff, Michael S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3168680/
https://ncbi.nlm.nih.gov/pubmed/21600214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2011.05.002
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