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Insights into the Role of Yeast eIF2A in IRES-Mediated Translation

Eukaryotic initiation factor 2A is a single polypeptide that acts to negatively regulate IRES-mediated translation during normal cellular conditions. We have found that eIF2A (encoded by YGR054w) abundance is reduced at both the mRNA and protein level during 6% ethanol stress (or 37°C heat shock) un...

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Autors principals: Reineke, Lucas C., Cao, Yu, Baus, Diane, Hossain, Nasheed M., Merrick, William C.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3168509/
https://ncbi.nlm.nih.gov/pubmed/21915340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024492
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