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Histone acetyltransferases regulate HIV-1 enhancer activity in vitro

Specific inhibitors of histone deacetylase, such as trichostatin A (TSA) and trapoxin (TPX), are potent inducers of HIV-1 transcription in latently infected T-cell lines. Activation of the integrated HIV-1 promoter is accompanied by the loss or rearrangement of a positioned nucleosome (nuc-1) near t...

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Detalhes bibliográficos
Main Authors: Sheridan, Philip L., Mayall, Timothy P., Verdin, Eric, Jones, Katherine A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC316802/
https://ncbi.nlm.nih.gov/pubmed/9407026
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