Persistent initiation of DNA replication and chromatin-bound MCM proteins during the cell cycle in cdc6 mutants

Faithful inheritance of genetic information requires that DNA be copied only once each cell cycle. Initiation of DNA replication involves the establishment of a prereplication complex (pre-RC) and subsequent activation by CDK/cyclins, converting the pre-RC to a post-RC. The origin recognition comple...

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Veröffentlicht in:	Genes Dev
Hauptverfasser:	Liang, Chun, Stillman, Bruce
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Cold Spring Harbor Laboratory Press 1997
Schlagworte:	Research Paper
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316796/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9407030/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.11.24.3375
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