Defining EMS and ENU Dose-Response Relationships Using the Pig-a Mutation Assay In Rats

In recent years, experimental evidence has accumulated that supports the existence of sublinear dose-response relationships at low doses of DNA reactive mutagens. However, creating the in vivo data necessary to allow for a more detailed dose-response modeling with the currently available tools might...

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Autori principali: Dobo, Krista L., Fiedler, Ronald D., Gunther, William C., Thiffeault, Catherine J., Cammerer, Zoryana, Coffing, Stephanie L., Shutsky, Thomas, Schuler, Maik
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167948/
https://ncbi.nlm.nih.gov/pubmed/21729764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrgentox.2011.06.005
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