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Differential Temporal and Spatial Progerin Expression during Closure of the Ductus Arteriosus in Neonates

Closure of the ductus arteriosus (DA) at birth is essential for the transition from fetal to postnatal life. Before birth the DA bypasses the uninflated lungs by shunting blood from the pulmonary trunk into the systemic circulation. The molecular mechanism underlying DA closure and degeneration has...

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Bibliographic Details
Main Authors: Bökenkamp, Regina, Raz, Vered, Venema, Andrea, DeRuiter, Marco C., van Munsteren, Conny, Olive, Michelle, Nabel, Elizabeth G., Gittenberger-de Groot, Adriana C.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167818/
https://ncbi.nlm.nih.gov/pubmed/21915271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023975
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