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Drosophila Double parked: a conserved, essential replication protein that colocalizes with the origin recognition complex and links DNA replication with mitosis and the down-regulation of S phase transcripts

We identified a Drosophila gene, double parked (dup), that is essential for DNA replication and belongs to a new family of replication proteins conserved from Schizosaccharomyces pombe to humans. Strong mutations in dup cause embryonic lethality, preceded by a failure to undergo S phase during the p...

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Dettagli Bibliografici
Pubblicato in:Genes Dev
Autori principali: Whittaker, Allyson J., Royzman, Irena, Orr-Weaver, Terry L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2000
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316778/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10898791/
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