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How and when should interactome-derived clusters be used to predict functional modules and protein function?

Motivation: Clustering of protein–protein interaction networks is one of the most common approaches for predicting functional modules, protein complexes and protein functions. But, how well does clustering perform at these tasks? Results: We develop a general framework to assess how well computation...

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Detalhes bibliográficos
Main Authors: Song, Jimin, Singh, Mona
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167697/
https://ncbi.nlm.nih.gov/pubmed/19770263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btp551
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