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Identifiability of isoform deconvolution from junction arrays and RNA-Seq

Motivation: Splice junction microarrays and RNA-seq are two popular ways of quantifying splice variants within a cell. Unfortunately, isoform expressions cannot always be determined from the expressions of individual exons and splice junctions. While this issue has been noted before, the extent of t...

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Bibliographic Details
Main Authors: Hiller, David, Jiang, Hui, Xu, Weihong, Wong, Wing Hung
Format: Artigo
Language:Inglês
Published: Oxford University Press 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167695/
https://ncbi.nlm.nih.gov/pubmed/19762346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btp544
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