Degradation of carboxy-terminal-tagged cytoplasmic proteins by the Escherichia coli protease HflB (FtsH)

Proteins with short nonpolar carboxyl termini are unstable in Escherichia coli. This proteolytic pathway is used to dispose of polypeptides synthesized from truncated mRNA molecules. Such proteins are tagged with an 11-amino-acid nonpolar destabilizing tail via a mechanism involving the 10Sa (SsrA)...

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Pubblicato in:	Genes Dev
Autori principali:	Herman, Christophe, Thévenet, Danielle, Bouloc, Philippe, Walker, Graham C., D’Ari, Richard
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Cold Spring Harbor Laboratory Press 1998
Soggetti:	Research Paper
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316767/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9573051/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.9.1348
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