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Signatures of DNA flexibility, interactions and sequence-related structural variations in classical X-ray diffraction patterns

The theory of X-ray diffraction from ideal, rigid helices allowed Watson and Crick to unravel the DNA structure, thereby elucidating functions encoded in it. Yet, as we know now, the DNA double helix is neither ideal nor rigid. Its structure varies with the base pair sequence. Its flexibility leads...

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Autors principals: Kornyshev, A. A., Lee, D. J., Wynveen, A., Leikin, S.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167609/
https://ncbi.nlm.nih.gov/pubmed/21593127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr260
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