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Signatures of DNA flexibility, interactions and sequence-related structural variations in classical X-ray diffraction patterns

The theory of X-ray diffraction from ideal, rigid helices allowed Watson and Crick to unravel the DNA structure, thereby elucidating functions encoded in it. Yet, as we know now, the DNA double helix is neither ideal nor rigid. Its structure varies with the base pair sequence. Its flexibility leads...

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Bibliografiske detaljer
Main Authors: Kornyshev, A. A., Lee, D. J., Wynveen, A., Leikin, S.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167609/
https://ncbi.nlm.nih.gov/pubmed/21593127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr260
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