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Experimental strategies for microRNA target identification

MicroRNAs (miRNAs) are important regulators of eukaryotic gene expression in most biological processes. They act by guiding the RNAi-induced silencing complex (RISC) to partially complementary sequences in target mRNAs to suppress gene expression by a combination of translation inhibition and mRNA d...

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Detalhes bibliográficos
Main Authors: Thomson, Daniel W., Bracken, Cameron P., Goodall, Gregory J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167600/
https://ncbi.nlm.nih.gov/pubmed/21652644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr330
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