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Innate C-H trifluoromethylation of heterocycles

Direct methods for the trifluoromethylation of heteroaromatic systems are in extremely high demand in nearly every sector of chemical industry. Here we report the discovery of a general procedure using a benchtop stable trifluoromethyl radical source that functions broadly on a variety of electron d...

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Detalhes bibliográficos
Main Authors: Ji, Yining, Brueckl, Tobias, Baxter, Ryan D., Fujiwara, Yuta, Seiple, Ian B., Su, Shun, Blackmond, Donna G., Baran, Phil S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167544/
https://ncbi.nlm.nih.gov/pubmed/21844378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1109059108
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