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WAVE regulatory complex activation by cooperating GTPases Arf and Rac1

The WAVE regulatory complex (WRC) is a critical element in the control of actin polymerization at the eukaryotic cell membrane, but how WRC is activated remains uncertain. While Rho GTPase Rac1 can bind and activate WRC in vitro, this interaction is of low affinity, suggesting other factors may be i...

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Bibliografische gegevens
Hoofdauteurs: Koronakis, Vassilis, Hume, Peter J., Humphreys, Daniel, Liu, Tao, Hørning, Ole, Jensen, Ole N., McGhie, Emma J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167530/
https://ncbi.nlm.nih.gov/pubmed/21844371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107666108
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