Targeted inactivation of plectin reveals essential function in maintaining the integrity of skin, muscle, and heart cytoarchitecture

Previous studies suggest that plectin, a versatile cytoskeletal linker protein, has an important role in maintaining the structural integrity of diverse cells and tissues. To establish plectin’s function in a living organism, we have disrupted its gene in mice. Plectin (−/−) mice died 2–3 days after...

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Bibliografiske detaljer
Main Authors: Andrä, Kerstin, Lassmann, Hans, Bittner, Reginald, Shorny, Sigrid, Fässler, Reinhard, Propst, Friedrich, Wiche, Gerhard
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 1997
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC316746/
https://ncbi.nlm.nih.gov/pubmed/9389647
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