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Disruption of downstream chromatin directed by a transcriptional activator

Promoter–proximal pausing during transcriptional elongation is an important way of regulating many diverse loci, including the human hsp70 gene. Pausing of RNA polymerase can be enhanced by chromatin structure. We demonstrate that activation of hsp70 leads to disruption of transcribed chromatin in f...

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Detalhes bibliográficos
Main Authors: Brown, Steven A., Kingston, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC316745/
https://ncbi.nlm.nih.gov/pubmed/9389644
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