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Error-prone bypass of certain DNA lesions by the human DNA polymerase κ

The Escherichia coli protein DinB is a newly identified error-prone DNA polymerase. Recently, a human homolog of DinB was identified and named DINB1. We report that the DINB1 gene encodes a DNA polymerase (designated polκ), which incorporates mismatched bases on a nondamaged template with a high fre...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ohashi, Eiji, Ogi, Tomoo, Kusumoto, Rika, Iwai, Shigenori, Masutani, Chikahide, Hanaoka, Fumio, Ohmori, Haruo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2000
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC316741/
https://ncbi.nlm.nih.gov/pubmed/10887153
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