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Subcellular localization and distribution of the reduced folate carrier in normal rat tissues

The reduced folate carrier (Rfc1; Slc19a1) mediated transport of reduced folates and antifolate drugs such as methotrexate (MTX) play an essential role in physiological folate homeostasis and MTX cancer chemotherapy. As no systematic reports are as yet available correlating Rfc1 gene expression and...

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Bibliografische gegevens
Hoofdauteurs: Hinken, M., Halwachs, S., Kneuer, C., Honscha, W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: PAGEPress Publications 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167344/
https://ncbi.nlm.nih.gov/pubmed/21556118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4081/ejh.2011.e3
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