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Subcellular localization and distribution of the reduced folate carrier in normal rat tissues

The reduced folate carrier (Rfc1; Slc19a1) mediated transport of reduced folates and antifolate drugs such as methotrexate (MTX) play an essential role in physiological folate homeostasis and MTX cancer chemotherapy. As no systematic reports are as yet available correlating Rfc1 gene expression and...

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Detalhes bibliográficos
Main Authors: Hinken, M., Halwachs, S., Kneuer, C., Honscha, W.
Formato: Artigo
Idioma:Inglês
Publicado em: PAGEPress Publications 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167344/
https://ncbi.nlm.nih.gov/pubmed/21556118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4081/ejh.2011.e3
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