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STERIC FACTORS MODERATE CONFORMATIONAL FLUIDITY AND CONTRIBUTE TO THE HIGH PROTON SENSITIVITY OF ROOT EFFECT HEMOGLOBINS
The structural basis of the extreme pH dependence of oxygen binding to Root effect Hbs is a long-standing puzzle in the field of protein chemistry. A previously unappreciated role of steric factors in the Root effect was revealed by a comparison of pH effects on oxygenation and oxidation processes i...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3167225/ https://ncbi.nlm.nih.gov/pubmed/21745602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2011.06.012 |
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