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Xamoterol impairs hippocampus-dependent emotional memory retrieval via G(i/o)-coupled β(2)-adrenergic signaling

Xamoterol, a partial β(1)-adrenergic receptor agonist, has been reported to impair the retrieval of hippocampus-dependent spatial reference memory in rats. In contrast, xamoterol restores memory retrieval in gene-targeted mice lacking norepinephrine (NE) and in a transgenic mouse model of Down syndr...

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Detalles Bibliográficos
Main Authors: Schutsky, Keith, Ouyang, Ming, Thomas, Steven A.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166789/
https://ncbi.nlm.nih.gov/pubmed/21878527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.2302811
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