Regulator of G protein signalling-1 (RGS1) selectively regulates gut T cell trafficking and colitic potential

The Regulator of G Protein Signaling 1 [RGS1] gene is associated with celiac disease, multiple sclerosis (MS) and Type I diabetes (T1D), which are all T cell-mediated pathologies. And yet there is no reported analysis of RGS1 biology in human T cells. This study shows that RGS1 expression is substan...

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Main Authors: Gibbons, Deena L., Abeler-Dörner, Lucie, Raine, Tim, Hwang, II-Young, Jandke, Anett, Wencker, Melanie, Deban, Livija, Rudd, Christopher E., Irving, Peter M., Kehrl, John H., Hayday, Adrian C.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166702/
https://ncbi.nlm.nih.gov/pubmed/21795595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100833
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