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N-myc can functionally replace c-myc in murine development, cellular growth, and differentiation

Members of the myc family of cellular oncogenes have been implicated as transcriptional regulators in pathways that govern cellular proliferation and death. In addition, N-myc and c-myc are essential for completion of murine embryonic development. However, the basis for the evolutionary conservation...

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Detalhes bibliográficos
Main Authors: Malynn, Barbara A., de Alboran, Ignacio Moreno, O'Hagan, Rónán C., Bronson, Roderick, Davidson, Laurie, DePinho, Ronald A., Alt, Frederick W.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC316670/
https://ncbi.nlm.nih.gov/pubmed/10837031
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