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Prolyl oligopeptidase induces angiogenesis both in vitro and in vivo in a novel regulatory manner

BACKGROUND AND PURPOSE: A serine protease, prolyl oligopeptidase (POP) has been reported to be involved in the release of the pro-angiogenic tetrapeptide acetyl-N-Ser-Asp-Lys-Pro (Ac-SDKP) from its precursor, 43-mer thymosin β4 (Tβ4). Recently, it was shown that both POP activity and the levels of A...

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Detalhes bibliográficos
Main Authors: Myöhänen, TT, Tenorio-Laranga, J, Jokinen, B, Vázquez-Sánchez, R, Moreno-Baylach, MJ, García-Horsman, JA, Männistö, PT
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166694/
https://ncbi.nlm.nih.gov/pubmed/21133893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.01146.x
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