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Notch signaling is essential for vascular morphogenesis in mice

The Notch gene family encodes large transmembrane receptors that are components of an evolutionarily conserved intercellular signaling mechanism. To assess the role of the Notch4 gene, we generated Notch4-deficient mice by gene targeting. Embryos homozygous for this mutation developed normally, and...

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Pubblicato in:Genes Dev
Autori principali: Krebs, Luke T., Xue, Yingzi, Norton, Christine R., Shutter, John R., Maguire, Maureen, Sundberg, John P., Gallahan, Daniel, Closson, Violaine, Kitajewski, Jan, Callahan, Robert, Smith, Gilbert H., Stark, Kevin L., Gridley, Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2000
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316662/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10837027/
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