Transcription factor Phox2 upregulates expression of norepinephrine transporter and dopamine β-hydroxylase in adult rat brains

Degeneration of the noradrenergic locus coeruleus (LC) in aging and neurodegenerative diseases is well documented. Slowing or reversing this effect may have therapeutic implications. Phox2a and Phox2b are homeodomain transcriptional factors that function as determinants of the noradrenergic phenotyp...

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Hlavní autoři: Fan, Yan, Huang, Jingjing, Duffourc, Michelle, Kao, Race L., Ordway, Gregory A., Huang, Rui, Zhu, Meng-Yang
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166407/
https://ncbi.nlm.nih.gov/pubmed/21763404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2011.07.005
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